What are Restylane® and Perlane®?

The Restylane® family of products includes Restylane and Perlane Both are cosmetic dermal fillers that replace lost volume and restore youthful contours to the skin to smooth away moderate to severe facial wrinkles and bids, such as the lines from your nose to the corners of your mouth (nasolabial folds).


How do I chose between Restylane® and Perlane®?

You don’t have to. In clinical trials, Restylane® and Perlane® were used in the same patients. The hyaluronic acid in both products is made by the same biotechnical process. The difference is in the gel particle size. Perlane gel particles are larger and designed for deeper injection than Restylane. Your doctor will decide which product is right for you.


How long do Restylane® products last?

Restylane® products are proven to deliver long-lasting results. Restylane lasts about six months. Perlane® lasts at least six months, in a majority of patients. Restylane Silk has been observed to last one year. The products’ patented stabilization technology helps maintain the cosmetic effect for those time periods.


Are Restylane®, Restylane Silk® and Perlane® FDA approved?

Yes. They are approved by the FDA for the treatment of moderate to severe facial wrinkles and folds, like the ones from your nose to the corners of your mouth. Ask your physician whether treatment is right for you.


What is the history of Restylane®?

Restylane®has been used in over 1.4 million treatments in the U.S. and is available in more than 70 countries. It is the most-studied cosmetic dermal filler in the world with dozens of publications in medical literature. Clinical studies showed no significant differences in the safety of Restylane and Perlane®.


What should patients do prior to treatment?

Restylane® and Perlane®require no pretesting, but you should take a few precautions before being treated. Avoid using aspirin, non-steroidal anti-inflammatory medications, St. John’s Wort, or high closes of Vitamin E supplements prior to treatment, because these may increase bruising or bleeding at the injection site. Also, if you have previously suffered from facial cold sores, discuss this with your doctor, who may prescribe a medication to minimize recurrence.


How are Restylane® products different than other hyaluronic acid-based products?

Restylane® and Perlane® contain no animal proteins. This limits any risk of animal-based disease transmission or allergic reaction. You should not use Restylane or Perlane if you have allergies to microorganisms known as gram-positive bacteria.


How do Restylane® and Perlane® products differ from Botox® Cosmetic?

Botox® Cosmetic and Restylane® are used to correct wrinkles in different ways. Restylane products are natural, cosmetic fillers injected into the skin, adding volume to smooth wrinkles such as the lines from your nose to the corners of your mouth (nasolabial folds). In contrast, Botox® relaxes the muscles that cause frown lines between your eye brows.


Important safety considerations of Restylane®

Restylane® restores volume and fullness to the skin to correct moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds). After your treatment, you might have some swelling and redness. This will normally last less than Seven days. Although rare, red or swollen small bumps may occur. If you have had herpes before, an injection can cause the herpes to return. In rare circumstances, the doctor may inject into a blood vessel, which can damage the skin. To avoid bruising and bleeding, you should not use Restylane® if you have recently used drugs that thin your blood or prevent clotting. If you are pregnant, breastfeeding, or under 18, you shouldn’t use Restylane.®

Restylane® should not he used by people with previous bad allergies, particularly to certain microorganisms known as gram positive bacteria, or by people with previous had allergies to drugs that have required in-hospital treatment. Restylane® should not be injected anywhere except the skin or just under the skin.

The use of Restylane® at the site of skin sores, pimples, rashes, hives, cysts, or infection should be postponed until healing is complete. Use of Restylane® in these instances could delay healing or make your skin problems worse.


Why wait?

If you want to enjoy a smoother, more youthful appearance, ask your doctor if Restylane® or Perlane® are right for you.